On-line monitoring of urea using enzymatic field effect transistors - LAAS - Laboratoire d'Analyse et d'Architecture des Systèmes Accéder directement au contenu
Article Dans Une Revue Sensors and Actuators B: Chemical Année : 2011

On-line monitoring of urea using enzymatic field effect transistors

William Sant
  • Fonction : Auteur
Pierre Temple-Boyer
Eric Chanié
  • Fonction : Auteur
Jérôme Launay

Résumé

Silicon and polymer-based technologies were developed in order to reach the industrial fabrication of disposable, mass-fabricated microsensors for the urea detection in liquid phase. The detection principle is based on pH-sensitive chemical field effect transistor (pH-ChemFET) microdevices. In order to realize an urea-sensitive enzymatic field effect transistor (urea-EnFET), studies involve the integration of an urease-based enzymatic layer by ink jet printing techniques, the packaging into a specific flow cell compatible with the liquid phase measurement, and the development of urea-EnFET/pH-ChemFET differential analysis technique. Thus, the urea detection properties were studied in EDTA-based and dialysate solutions, evidencing good sensitivity in concentration ranges appropriate to human kidney failure. Finally, the whole analysis system was successfully tested for the continuous monitoring of urea in artificial dialysis conditions.
Fichier principal
Vignette du fichier
manuscript_pUreaEnFET.pdf (762.3 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-01511364 , version 1 (20-04-2017)

Identifiants

Citer

William Sant, Pierre Temple-Boyer, Eric Chanié, Jérôme Launay, Augustin Martinez. On-line monitoring of urea using enzymatic field effect transistors. Sensors and Actuators B: Chemical, 2011, 160 (1), pp.59 - 64. ⟨10.1016/j.snb.2011.07.012⟩. ⟨hal-01511364⟩
41 Consultations
91 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More