AI applications have never been as popular as today. The enthusiasm of all branches of the industry is in tune and agrees to say that AI technologies can lift many industrial locks for customer value creation, productivity improvement, and insight discovery. Huge business opportunities are expected in this process. Numerous applications are also foreseen in medicine and heath care, agriculture and environment, transport/mobility, and energy domains. Faced with this expectation, where does the diagnosis community situate itself ? In this talk, I will focus on engineering and process applications and will identify some requests and needs in these domains. I will then focus on diagnosis reasoning and explain how existing diagnosis theories can bring their contribution based on the presentation of some applications that address specific needs in these domains. I will conclude my talk by drawing my picture of what is still missing to satisfy the current expectations.