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Micro Particle Sizing Using Hilbert Transform Time Domain Signal Analysis Method in Self-Mixing Interferometry

Abstract : The present work envisages the development of a novel and low-cost self-mixing interferometry (SMI) technology-based single particle sensing system in a microchannel chip for real time single micro-scale particle sizing. We proposed a novel theoretical framework to describe the impulse SMI signal expression in the time domain induced by a flowing particle. Using Hilbert transform, the interferometric fringe number of the impulse SMI signal was retrieved precisely for particle size discrimination. For the ease of particle sensing, a hydrodynamic focusing microfluidic channel was employed by varying the flow rate ratio between the sample stream and the sheath liquid, and the particle stream of a controllable width was formed very easily. The experimental results presented good agreement with the theoretical values, providing a 300 nm resolution for the particle sizing measurement
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https://hal.laas.fr/hal-02794527
Contributor : Julien Perchoux <>
Submitted on : Friday, June 5, 2020 - 11:27:48 AM
Last modification on : Friday, September 25, 2020 - 3:08:03 PM

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Yu Zhao, Menglei Zhang, Chen Zhang, Wuxiong Yang, Tao Chen, et al.. Micro Particle Sizing Using Hilbert Transform Time Domain Signal Analysis Method in Self-Mixing Interferometry. Applied Sciences, MDPI, 2019, 9 (24), pp.5563. ⟨10.3390/app9245563⟩. ⟨hal-02794527⟩

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