In this paper, the invertibility of an interconnected system that consists of two dynamic subsystems was studied. It can be viewed as the distinguishability of the impacts of local input on the final global output, that is to say, whether the input at the local level can be recovered uniquely under a given output at the global level and initial state. The interconnected system constitutes two dynamic subsystems connected in a cascade manner. In order to guarantee the invertibility of the studied system, a necessary and sufficient condition was established. On the condition that both individual subsystems are invertible, the invertibility of the global system can be guaranteed. In order to recover the local input which generates a given global output, an algorithm was proposed for the studied interconnected system. Numerical examples were considered to confirm the effectiveness and robustness of the proposed algorithm