A. , A. , and M. M. Ssssss, An overview of TCI & TIVA, pp.978-90, 2007.

A. , A. R. , V. Mmmm, T. Dd, M. M. Ssss et al., « Pharmacokinetic models for propofol-Deening and illuminating the devil in the detail, British Journal of Anaesthesia, vol.1031, pp.26-37, 2009.

A. , A. R. Et, and G. N. Kkkkk, « Closed-loop control of propofol anaesthesia using bispectral index : Performance assessment in patients receiving computercontrolled propofol and manually controlled remifentanil infusions for minor surgery, British Journal of Anaesthesia, vol.90, pp.737-741, 2003.

A. , A. R. , N. Sss, and G. N. Kkkkk, « Closed-loop control of anesthesia using Bispectral index : performance assessment in patients undergoing major orthopedic surgery under combined general and regional anesthesia. » In : Anesthesiology 96, pp.67-73, 2002.

A. , A. R. , R. Dd-kkkkkk, and M. Ssssss, Closed loop anesthesia : are we getting close to nding the Holy Grail ? Optimal control : an introduction to the theory and its applications, 2011.

B. , R. , M. V. , D. Mmmmmmmmm, E. Ssss et al., « Heart rate variability in subjects with diierent hypnotic susceptibility receiving nociceptive stimulation and suggestions of analgesia, 2005.

B. , P. , B. Cccccc, R. Ss, M. Ccccccc et al., Clinical Anesthesia, p.9781451122978, 2011.

B. , L. , E. Eeeeeeee, J. M. Eee, E. Ccccccccc et al., « EEect site concentrations of remifentanil and pupil response to noxious stimulation, British Journal of Anaesthesia, vol.913, pp.347-352, 2003.

B. , C. Et, and A. Ssssss, « A looped-functional approach for robust stability analysis of linear impulsive systems, Systems & Control Letters, vol.6110, pp.980-988, 2012.

B. , C. J. , W. Kkkkkk, D. Mmmmm, E. Ccccc et al., « Wavelet transform cardiorespiratory coherence detects patient movement during general anesthesia, Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp.6114-6117, 2011.

C. , D. V. , J. M. Lllll, and B. A. Cccc, « Robust control of depth of anesthesia based on H ? design, Archives of Control Sciences, vol.23, issue.1, pp.41-59, 2013.

C. , F. , C. D. Pppppp, and P. Ffffff, « Discontinuities and hysteresis in quantized average consensus, Automatica, vol.479, pp.1916-1928, 2011.

C. , M. , D. Eeeeeee, J. Pppppp, L. Mmmmm et al., « An evaluation of using population pharmacokinetic models to estimate pharmacodynamic parameters for propofol and bispectral index in children, pp.83-93, 2011.

C. , P. A. , S. M. Kkkkkkkk, I. Lll, and J. M. Ggggggg, « Improving the Safety of Patient-Controlled Analgesia Infusions with Safety Interlocks and Closed-Loop Control, Joint Workshop on High Conndence Medical Devices, Software, and Systems and Medical Device Plug-and-Play Interoperability, pp.149-150, 2007.

C. , G. C. , J. Ddd, N. H. Kk, J. P. et al., « Dose requirements of ICI 35,868 (Propofol, 'Diprivan') in a new formulation for induction of anaesthesia, pp.39-1168, 1984.

D. Jjjjjjjjjj, J. , D. Rrrrrr, J. Nnnnnnnn, M. Jjjjjj et al., « Heart rate variability analysis as an index of emotion regulation processes : Interest of the Analgesia Nociception Index (ANI), Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), pp.3432-3435, 2012.

D. Jjjjjjjjjj, J. , M. Ddddddddd, M. Jjjjjj, N. Kkkkkkkk et al., Automated analgesic drugs delivery guided by vagal tone evaluation : Interest of the Analgesia Nociception Index (ANI), 2013.

D. , H. Et, and B. Mmmmmmm, « Modeling of Pharmacokinetic / Pharmacodynamic (PK/PD) Relationships : Concepts and Perspectives ». English, Pharmaceutical Research, vol.16, issue.2, pp.176-185, 1999.

D. , G. A. , A. Mmmmmmmm, and J. M. Aaaaaaaaa, « Robust control of depth of anesthesia, International Journal of Adaptive Control and Signal Processing, vol.235, pp.435-454, 2009.

F. , F. , F. Ggg, and S. T. , « Stabilization of continuous-time linear systems subject to input quantization, Automatica, vol.58, pp.167-172, 2015.

F. , M. , I. , S. T. , and M. Mmmmmmmmmm, « Invariant based control of induction and maintenance phases for anesthesia, 6th IFAC Conference on Foundations of Systems Biology in Engineering, 2016.

F. , J. , D. Eeeeeee, J. Ggggg, and . Jj, « On the Tracking Problem for Linear Systems Subject to Control Saturation, Proceedings of the 17th world congress 1, pp.14168-14173, 2008.

F. , E. , Y. Ss, G. Sssssssss, M. Aaaaa et al., « A hypnosis control system using a model predictive controller with online identiication of individual parameters, Proceedings of 2005 IEEE Conference on Control Applications, 2005.

F. , E. Et, and K. Tttttttt, « A Hypnosis and Analgesia Control System Using a Model Predictive Controller in Total Intravenous Anesthesia During Day-case Surgery, Stress : The International Journal on the Biology of Stress, pp.223-226, 2010.

G. , J. C. , R. H. Et, and J. Bbbbbbbbb, « H 2 and H ? robust output feedback control for continuous time polytopic systems, pp.1541-1549, 2007.

G. Sss-jj, J. M. , I. , A. Ssssss, and S. T. , « Regional Stability Analysis of Discrete-Time Dynamic Output Feedback Under Aperiodic Sampling and Input Saturation, IEEE Transactions on Automatic Control, 2016.

H. , W. , J. Bbbbbb, and J. J. Ii, « Neuroadaptive Output Feedback Control for Automated Anesthesia with Noisy EEG Measurements, IEEE Transaction On Control Systems Technology, vol.19, issue.2, pp.311-326, 2011.

H. , W. M. , T. Hh, and J. M. Bbbbbb, « Adaptive control for non-negative and compartmental dynamical systems with applications to general anesthesia, International Journal of Adaptive Control and Signal Processing, vol.173, pp.209-235, 2003.

H. , W. M. , V. Ccccccccccc, and Q. Hhh, Nonnegative and compartmental dynamical systems, 2010.

H. , W. M. , J. M. Bbbbbb, B. Ggggggg, and A. R. , « Clinical decision support and closed-loop control for intensive care unit sedation, Asian Journal of Control, vol.155, pp.317-339, 2013.

H. , K. Van, G. Dddddd, K. Sss, C. Pppppppp et al., « Design and clinical evaluation of robust PID control of propofol annesthesia in children, IEEE Transactions on Control Systems Technology 22.2, pp.491-501, 2014.

I. , C. M. , R. D. Kkkkkk, B. C. , T. D. Ssss et al., « Robust predictive control strategy applied for propofol dosing using BIS as a controlled variable during anesthesia, IEEE Transactions on Biomedical Engineering, vol.559, pp.2161-2170, 2008.

J. , J. W. Et, and P. S. Sssss, « Development and Clinical Application of Electroencephalographic Bispectrum Monitoring, Anesthesiology 93.5, pp.1336-1344, 2000.

K. , T. , S. K. , S. , T. Ii et al., « The eeect of fentanyl on sevoourane requirements for somatic and sympathetic responses to surgical incision. » In : Anesthesiology 90, pp.398-405, 1999.

K. and T. E. Krieger, The History of Surgical Anesthesia, pp.978-0882755700, 1978.

K. , P. V. , H. K. Kkkkkk, and J. O-'rrrrr, Singular perturbation methods in control : analysis and design. T. 29, pp.323-324, 1987.

L. , J. M. , D. V. Cccccc, B. A. Cccc, L. A. et al., « Robust control of maintenance-phase anesthesia, IEEE Control Systems Magazine 34.6, pp.24-38, 2014.

M. , P. O. , S. V. , J. Hhhhhhhh, D. A. Ttttttt et al., « Population Pharmacokinetics of AlfentanilThe Average Dose-Plasma Concentration Relationship and Interindividual Variability in Patients, Anesthesiology 66.1, pp.3-12, 1987.

M. , B. , M. W. , N. Mmmm, and G. N. Kkkkk, « Pharmacokinetic model driven infusion of propofol in children, » In : British journal of anaesthesia, vol.67, pp.41-48, 1991.

M. , D. M. , P. M. Ccccccc, M. M. Ssssss, T. Dd-ssss et al., « Feasibility study for the administration of remifentanil based on the diierence between response entropy and state entropy, British Journal of Anaesthesia 98, pp.785-791, 2007.

M. , T. , H. Mm, P. Ll, and S. Eeeeeee, « Hipocrates : a robust system for the control of neuromuscular blockade, Journal of clinical montitoring and computing 18, pp.265-273, 2004.

M. , R. Et, and R. Ss, Basics of Anesthesia, p.9780443068010, 2007.

M. , S. E. , G. N. Kkkkk, and S. Ssssss, « Propofol sparing eeect of remifentanil using closed-loop anaesthesia, British Journal of Anaesthesia, vol.905, pp.623-629, 2003.

M. , C. F. , T. W. Sssssssss, and S. L. Ssssss, « Pharmacokinetics and pharmacodynamics of remifentanil.Model application, Anesthesiology 86.1, pp.24-33, 1997.

P. , D. Y. , T. S. Ddd, and T. R. , « Designing and implementation of fuzzy logic based automatic system to estimate dose of anesthesia, The next Generation inforlation Technology Summit, pp.95-102, 2013.

R. , A. E. , M. J. Ppppp, J. R. Sssss, A. P. Mmcccc et al., « Remifentanil?midazolam sedation for paediatric patients receiving mechanical ventilation after cardiac surgery ?, British Journal of Anaesthesia 99, pp.252-261, 2007.

R. , F. , D. Sssss, R. Hhhhhh, C. Iiiiiii et al., « Estimating the time-delay for predictive control in general anesthesia, Control and Decision Conference (CCDC), 2010.

R. , H. , J. S. , J. F. Cccc, B. Lll et al., « Pain relief using smart technology : an overview of a new patient-controlled analgesia device. » In : IEEE transactions on information technology in biomedicine : a publication of the, IEEE Engineering in Medicine and Biology Society, vol.31, pp.20-27, 1999.

S. , C. , A. Ggggggggg, M. Mmmmmm, C. Bbbbbbb et al., « Perioperative closed-loop control of analgesia in humans, Annual Reports of the Research Reactor Institute, p.449, 2001.

S. , C. , P. Ggggggg, and M. Ccccccc, « Multiobjective output-feedback control via LMI optimization, IEEE Transactions on Automatic Control, vol.42, pp.896-911, 1997.

S. , T. W. , M. C. Et, and S. D. , « The eeect compartment concept in pharmacodynamic modelling, Anesthetic Rharmacology Review, vol.2, pp.204-219, 1994.

S. , T. W. , C. F. Mmmm, P. L. Gggggg, C. Aaaaaaaa et al., « The innuence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers, pp.1170-1182, 1998.

S. , P. , E. Llll, I. Rrrrrr, P. W. et al., « A multicenter study of bispectral electroencephalogram analysis for monitoring anesthetic eeect, Anesthesia & Analgesia 84, pp.891-899, 1997.

S. , L. , D. Ss, S. V. , R. Mmmmmm et al., « Simultaneous modeling of pharmacokinetics and pharmacodynamics : application to d-tubocurarine, Clinical pharmacology and therapeutics 25, pp.358-371, 1979.

S. , J. S. , Y. R. Www, C. Y. Ddd, and W. Z. Sss, « Fuzzy pain demand index from an i-pain system for assessment of postoperative pain via patient-controlled analgesia using a multilayer hierarchical structure, Proceedings of the 2nd International Conference on Pervasive Computing Technologies for Healthcare, pp.152-155, 2008.

S. , J. Et, and I. Iiiiii, « Population pharmacokinetic of propofol -A multicenter study, Anesthesiology 92.3, pp.727-738, 2000.

S. , M. M. , T. Mmmmmmmm, and T. W. , « Nonlinear adaptive control of the NeuroMuscular Blockade in anesthesia, 50th IEEE Conference on Decision and Control and European Control Conference, pp.41-46, 2011.

S. , D. E. , A. J. Ff, and R. G. Bbbbbbbb, « Anesthesiology ». In : The clinical application of automatic anesthesia 12, p.574582, 1951.

S. , K. , J. O. Hhhh, G. A. Dddddd, and J. M. Aaaaaaaaa, « Individualized PID control of depth of anesthesia based on patient model identiication during the induction phase of anesthesia, IEEE Conference on Decision and Control, pp.855-860, 2011.

S. , K. , K. V. Hhhhhhh, G. A. Dddddd, H. T. et al., « Closed-Loop Anesthesia in Children using a PID controller : A Pilot Study, IFAC Conference on advances in PID Control, pp.3-8, 2012.

S. , M. M. , T. Dd-ssss, L. F. Vvvvvvvvvvv, S. V. Dd et al., « Comparison of closed-loop controlled administration of propofol using Bispectral Index as the controlled variable versus "standard practice, pp.6-17, 2001.

S. , M. M. , T. Dd-ssss, S. Gggggg, A. R. Aaaaaaa et al., « Performance Evaluation of Two Published Closed-loop Control Systems Using Bispectral Index MonitoringA Simulation Study, Anesthesiology, vol.1003, pp.640-647, 2004.

S. , M. M. , C. V. , M. Hhhhh, K. Uuuuuu et al., « Changes in a surgical stress index in response to standardized pain stimuli during propofol-remifentanil infusion, British Journal of Anaesthesia 99, pp.359-367, 2007.

T. , S. , and F. Ggg, « Control design for quantized linear systems with saturations, IEEE Transactions on Automatic Control, vol.57, pp.1883-1889, 2012.

T. , S. , C. Pppppp, and C. Bbbbb, « Output tracking problem for systems with input saturations via nonlinear integrating actions, Int. J. of Robust and Nonlinear Control, vol.10, issue.6, pp.489-512, 2000.

T. , S. , G. Gggggg, J. M. Ggggg, and I. Jj, Stability and Stabilization of Linear Systems with Saturating Actuators, 2011.

T. , A. R. , R. Gggggg, and R. G. Sssssssss, Hybrid Dynamical Systems : Modeling, Stability and Robustness, 2012.

U. , T. , K. Mmmmmmmmm, H. W. , T. Nnnn et al., « Analysis of heart rate variability as an index of noncardiac surgical stress, Heart and Vessels 23, pp.53-59, 2008.

W. , B. , S. W. , E. Y. Nnnnn-39s?45s, S. et al., « Pharmacokinetics, pharmacodynamics and dose-response relationships of atracurium administered i.v » « Population pharmacokinetics of a propofol bolus administered in patients with major burns, In : British journal of anaesthesia, vol.55, pp.36-39, 1983.

Y. , P. C. Et, and J. C. , « An approach to the linear multivariable servomechanism problem ?, International Journal of Control, vol.155, pp.961-979, 1972.

Z. , S. , I. , S. T. , G. Gggggg et al., « New approach for the control of anesthesia based on dynamics decoupling, 9th IFAC Symposium on Biological and Medical Systems, 2015.

Z. , S. , I. , S. T. , and M. Mmmmmmmmmm, « Controler design for analgesia with quantized pupil size variation output and saturating infusion rate, Nonlinear control system, 2016.

Z. , S. , I. , S. T. , G. Gggggg et al., « Nouvelle approche pour la commande de l'anesthésie basée sur un découplage de la dynamique, 2016.