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Probing electrical activity of single neurons based on 1D nanostructures: from extra to intracellular interfacing.

Abstract : The struggle against neurodegenerative diseases is one of the major challenges in the near future and the global understanding of these diseases goes through a better expertise at the single cell level of basic mechanisms involved in neuronal networks. We need to investigate closer to the cellular material and in this way, miniaturization of electronic components and emergence of nano-biotechnology open new perspectives. Indeed, we are now able to fabricate high sensitive nano-devices to follow neuronal activities. Here, we will present two different approaches to interface neurons, a first one based on a nano-FET for extracellular recordings and a second one using vertical nanowire arrays (nano-electrodes) for intracellular measurements.
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https://hal.laas.fr/hal-01462968
Contributor : Adrien Casanova <>
Submitted on : Tuesday, June 27, 2017 - 3:33:32 PM
Last modification on : Tuesday, February 18, 2020 - 3:32:02 PM
Long-term archiving on: : Tuesday, December 12, 2017 - 12:10:42 PM

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  • HAL Id : hal-01462968, version 1

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Adrien Casanova, Marie-Charline Blatché, Fabrice Mathieu, Aurélie Lecestre, Cécile Ferré, et al.. Probing electrical activity of single neurons based on 1D nanostructures: from extra to intracellular interfacing.. 11th IEEE Nanotechnology Materials and Devices Conference (NMDC), Oct 2016, Toulouse, France. 2p. ⟨hal-01462968⟩

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